S. Kettering kinh mat thoi trang J

Mat kinh hang hieu 7

Steaks Meat and Blood Sausage Propel the Creation of Azoxymethane-Induced Mucin-Depleted Foci and Aberrant

Crypt Foci in Mice Colons1,2
ABSTRACT
KEY WORDS: * intestines carcinogenesis * heme * lipoperoxidation * red meat * hen
The present learn was created to try on the theory which heme within the nutriment matrix could propel colon carcinogenesis. The diets use within former animal studies (3-13) included high degrees of calcium; we supposed which calcium inhibited the marketing result of red meat. Three models of meat were selected with distinct heme contents: hen, steaks, and black pudding. A 4th diet, comprising purified hemoglobin, was contained as a control which included the equivalent emphasis of heme as the steaks diet. The myoglobin in steaks is really so close in structure to hemoglobin.
MATERIALS And techniques
RESULTS
Dialog
This learn ‘s the first to imply that meat could specifically propel colon carcinogenesis. As well as that, the marketing result was stronger than other marketing agents (30) and obviously linked with the heme emphasis in meat. This learn was done with a low-calcium diet comprising 60% meat and 5% effortlessly oxidized petroleum. We used 2 putative precancerous endpoints: the set forth ACF and the lately described MDF. Heme within the diet brought about ACF and MDF promo within the colon. The low-heme chicken-based diet didn’t propel MDF, but grown the dig this ACF number.
kinh thoi trang ACKNOWLEDGMENTS
We thank Xavier Blanc (UPAE) for the preparation of experimental diets,. Termont for the assay of cytolytic activity of fecal essential fluids on erythrocytes, Florencia Vallenari for the assay of heme in poo and fecal essential fluids, Marie-Claude Nicot for the assay of calcium and iron in ham, and Raymond Gazel and Florencia Prejudice Y Estrada for the care of the animals.
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Manuscript earned 4 Might 2004. Preliminary review concluded 24 Might 2004. Revision approved 2 Aug 2004.
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[Author Network]
Fabrice Pierre,3 Amanda Freeman,* Sylviane Tach%u00e9, Roelof Truck der Meer,[dagger] and Denis E. Corpet
Ecole Nationale V%u00e9t%u00e9rinaire Toulouse, UMR INRA-ENVT X%u00e9nobiotiques, 23 Capelles, 31076 Toulouse, France; * Dept of Veterinarian Science, College of Melbourne, Melbourne, Australia; and [knife] Wageningen Center for Nutriment Sciences, NIZO Nutriment Research, 6710 BA Ede, Holland
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3 To whom letter must be addressed..